Set on approximately 35 picturesque acres bordering the Piscassic River, 295 Wadleigh Falls Road offers a rare blend of privacy, space, and New England charm. This expansive 4-bedroom, 4-bath home features over 3,300 square feet of living space with flexible living areas across multiple levels, including a private lower-level guest suite with full bath and a bonus room over the garage. The home is designed for both everyday comfort and entertaining, featuring a spacious kitchen with newer appliances, multiple gathering spaces, gas fireplaces, and a wood-burning fireplace. Thoughtful systems and amenities include multi-zone heating and cooling, a whole-house generator, security system, heated 3-car garage, and abundant storage throughout. Outside, enjoy open fields, mature landscaping, river frontage, and the peaceful setting of historic Newmarket farm country. The property provides access to endless outdoor recreation while remaining conveniently located just minutes to downtown Newmarket, Portsmouth, and the Seacoast beaches.